What Does ORF Stand For?

ORF stands for Open Reading Frame DNA Sequence

ORF, or Open Reading Frame DNA Sequence, refers to a continuous stretch of nucleotide sequences within a DNA strand that has the potential to be translated into a protein. An ORF begins with a start codon and ends with a stop codon, representing a sequence that does not contain any intervening stop codons. Identifying ORFs is essential in genetics and molecular biology as it helps determine the protein-coding potential of genes and is crucial for annotating genomes.

Added on 14th April 2008 | Last edited on 16th June 2025 | Edit Acronym

Other Meanings for ORF