What Does APC Stand For?
APC stands for Anaphase Promoting Complex
The Anaphase Promoting Complex (APC) is a multifunctional E3 ubiquitin ligase crucial for the regulation of the cell cycle. It plays a pivotal role in promoting the transition from metaphase to anaphase by targeting specific cell cycle proteins for degradation via the ubiquitin-proteasome pathway. This action ensures accurate chromosome segregation and is essential for maintaining genomic stability. Additionally, APC is involved in various cellular processes beyond the cell cycle, including apoptosis and DNA damage response. Its function is tightly regulated, highlighting its significance in cellular proliferation and tumorigenesis.
Added on 14th April 2008 | Last edited on 16th June 2025 | Edit Acronym