What Does APCI Stand For?

APCI stands for Atm Pressure Chem Ionization

APCI, or Atmospheric Pressure Chemical Ionization, is a soft ionization technique used in mass spectrometry. It enables the generation of ions from gaseous analytes at atmospheric pressure, facilitating the analysis of thermally labile and polar compounds. APCI employs a corona discharge to produce ions from a solvent and analyte mixture, making it particularly valuable for detecting a wide range of chemical substances in complex matrices. This method enhances sensitivity and selectivity in quantitative and qualitative analyses across various applications, including pharmaceutical and environmental testing.