What Does APL Stand For?
APL stands for Acute Promyelocytic Leukemia
APL, or Acute Promyelocytic Leukemia, is a subtype of acute myeloid leukemia characterized by the accumulation of promyelocytes in the bone marrow and blood. It is associated with a specific genetic mutation involving the promyelocytic leukemia (PML) gene and the retinoic acid receptor alpha (RARA) gene. APL is notable for its clinical presentation, which may include coagulopathy leading to bleeding complications. Treatment often involves targeted therapies such as all-trans retinoic acid (ATRA) and arsenic trioxide, which have significantly improved outcomes for patients. Early diagnosis and intervention are critical for effective management of this condition.
Added on 14th April 2008 | Last edited on 16th June 2025 | Edit Acronym