What Does APUD Stand For?

APUD stands for Amine Precursor Uptake And Decarboxylation

APUD, or Amine Precursor Uptake And Decarboxylation, refers to a physiological process in which specific cells actively take up amine precursors and subsequently decarboxylate them to produce biogenic amines. This mechanism is crucial for the synthesis of neurotransmitters and hormones, playing a vital role in various biological functions, including regulation of mood, cardiovascular activities, and gastrointestinal motility. The APUD system is especially significant in neuroendocrine cells, where it contributes to the intricate interplay of signaling molecules in the body.