What Does BCMA Stand For?

BCMA stands for B Cell Maturation Antigen

BCMA, or B Cell Maturation Antigen, is a protein primarily expressed on the surface of B cells and plasma cells. It plays a crucial role in regulating B cell survival, differentiation, and activation. BCMA is of significant interest in immunology and oncology, particularly as a therapeutic target in multiple myeloma, where it is utilized for developing targeted treatments such as monoclonal antibodies and CAR T-cell therapies. Its expression is associated with the maintenance of long-lived plasma cells and contributes to the immune response.