What Does CFTR Stand For?

CFTR stands for Cystic Fibrosis Transmembrane Conductance Regulator

CFTR, or Cystic Fibrosis Transmembrane Conductance Regulator, is a protein that functions as a channel for chloride ions across epithelial cell membranes. It plays a critical role in maintaining the balance of salt and water on epithelial surfaces, particularly in the lungs, pancreas, and intestines. Mutations in the CFTR gene lead to cystic fibrosis, a genetic disorder characterized by thick, sticky mucus production, resulting in respiratory and digestive issues. Understanding CFTR's function is essential for developing targeted therapies for cystic fibrosis and related conditions.