What Does CLP Stand For?
CLP stands for Cecal Ligation And Puncture
Cecal Ligation And Puncture (CLP) is a widely utilized experimental procedure in biomedical research, particularly in the study of sepsis and inflammatory conditions. This model involves the ligation of the cecum, followed by puncturing it to induce localized infection and subsequent systemic inflammatory response. CLP mimics the pathophysiology of human sepsis, allowing researchers to investigate disease mechanisms, test therapeutic interventions, and evaluate potential treatments in a controlled setting. The procedure is notable for its reproducibility and relevance in studying host responses to bacterial infections.
Added on 14th April 2008 | Last edited on 17th June 2025 | Edit Acronym