What Does CPEO Stand For?

CPEO stands for Chronic Progressive External Ophthalmoplegia

CPEO, or Chronic Progressive External Ophthalmoplegia, is a rare neuromuscular disorder characterized by the gradual weakening and paralysis of the eye muscles, resulting in difficulties with eye movement and often leading to the drooping of eyelids. It primarily affects individuals in adulthood and can be associated with mitochondrial dysfunction, contributing to systemic symptoms such as muscle weakness and fatigue. Diagnosis typically involves clinical evaluation, neuroimaging, and genetic testing to identify underlying mitochondrial mutations. Management focuses on symptomatic relief and supportive care.