What Does CSGE Stand For?

CSGE stands for Conformation Sensitive Gel Electrophoresis

Conformation Sensitive Gel Electrophoresis (CSGE) is a specialized analytical technique used to separate nucleic acids based on their three-dimensional structures rather than solely on their size. This method enhances the detection of conformational variants, such as mutations or structural discrepancies in DNA and RNA, by employing a gel matrix that discriminates between different conformations during the electrophoresis process. CSGE is particularly valuable in genomics and molecular biology for applications in mutation screening, fragment analysis, and the study of nucleic acid folding and interactions.