What Does CTLA Stand For?

CTLA stands for Cytotoxic T Lymphocyte Antigen

CTLA, or Cytotoxic T Lymphocyte Antigen, refers to a key protein involved in the regulation of immune responses. Primarily expressed on the surface of T cells, CTLA plays a crucial role in modulating T cell activation and function. It serves as a co-stimulatory molecule that enhances immune responses against tumors and infections while also contributing to immune tolerance, preventing autoimmunity. CTLA has significant implications in cancer immunotherapy, with therapies targeting this pathway demonstrating effectiveness in treating various malignancies.