What Does DEPC Stand For?

DEPC stands for Diethyl Pyrocarbonate

DEPC, or Diethyl Pyrocarbonate, is a chemical compound with the formula C6H10O5. It is commonly used as a reagent in molecular biology to modify nucleic acids, specifically to inactivate RNases, thereby protecting RNA during experiments. DEPC serves as an effective agent for the preservation of RNA integrity, making it crucial in research applications involving RNA extraction and analysis. Its utility in laboratory protocols is underscored by its ability to crosslink and modify biomolecules while maintaining the functional properties necessary for downstream applications. Safety and handling precautions are essential due to its potential hazards.