What Does EGFR Stand For?

EGFR stands for Epidermal Growth Factor Receptor

EGFR, or Epidermal Growth Factor Receptor, is a cell surface protein that plays a crucial role in cellular signaling pathways regulating cell proliferation, differentiation, and survival. It is part of the epidermal growth factor receptor family and is activated by binding to specific ligands, leading to a cascade of downstream effects that influence various physiological processes. EGFR is of significant interest in oncology, as mutations or overexpression of this receptor are often implicated in the development and progression of several types of cancer, making it a key target for therapeutic intervention.