What Does FLIP Stand For?

FLIP stands for FLICE Inhibitory Protein

FLIP, or FLICE Inhibitory Protein, is a regulatory protein that plays a crucial role in apoptosis, or programmed cell death. It functions by inhibiting the activity of cysteine proteases, specifically the caspases that are essential for the apoptotic signaling cascade. By modulating these pathways, FLIP contributes to cell survival and can influence the outcomes in various biological processes, including immune responses and cancer progression. Its expression and function are of significant interest in understanding therapeutic strategies targeting cell death in diseases.

Other Meanings for FLIP