What Does FPGS Stand For?

FPGS stands for Folylpolyglutamate Synthetasepar

FPGS, or Folylpolyglutamate Synthetasepar, is an enzyme that catalyzes the formation of polyglutamated forms of folate coenzymes from monoglutamate precursors. This enzyme plays a crucial role in folate metabolism, enhancing the retention and biological activity of folate derivatives within cells. FPGS is important in various physiological processes, including DNA synthesis and repair, and has implications in pharmacology, particularly in the efficacy of certain chemotherapeutic agents that target folate pathways.