What Does GVBD Stand For?

GVBD stands for Germinal Vesicle Breakdown

GVBD, or Germinal Vesicle Breakdown, refers to the process during oocyte maturation where the germinal vesicle, which is the large central vesicle containing the oocyte's nucleus, disintegrates. This event is crucial for the transition from the prophase stage of meiosis to the metaphase stage, enabling the oocyte to resume its development and prepare for fertilization. GVBD is a key indicator of oocyte viability and developmental competence in reproductive biology.