What Does HAMA Stand For?

HAMA stands for Human Anti Mouse Antibody

HAMA, or Human Anti-Mouse Antibody, refers to antibodies produced by the human immune system in response to mouse-derived proteins. This immune reaction can occur when humans are exposed to monoclonal antibodies or other mouse proteins used in therapeutic or research settings. The presence of HAMA can impact the efficacy and safety of mouse-derived therapeutics, leading to altered drug metabolism, reduced efficacy, or adverse immune responses. Monitoring HAMA levels is important in clinical studies and therapeutic applications to ensure patient safety and treatment effectiveness.