What Does HDAC Stand For?

HDAC stands for Histone Deacetylase

Histone Deacetylase (HDAC) is a class of enzymes that play a crucial role in the regulation of gene expression by removing acetyl groups from histone proteins. This deacetylation process leads to a more compact and transcriptionally inactive chromatin structure, thereby repressing gene activity. HDACs are involved in various cellular processes, including cell cycle regulation, differentiation, and response to stress. They have been implicated in numerous diseases, including cancer, making them important targets for therapeutic intervention.