What Does HIC Stand For?

HIC stands for Hydrophobic Interaction Chromatography

HIC, or Hydrophobic Interaction Chromatography, is a specialized chromatographic technique used to separate and purify proteins and biomolecules based on their hydrophobic properties. This method exploits the differences in the hydrophobicity of molecules by employing a solid-phase medium with hydrophobic functional groups, allowing for the selective binding of hydrophobic regions of proteins when subjected to high salt concentrations. Upon dilution of the salt, proteins elute based on their varying hydrophobic interactions, making HIC a powerful tool for protein purification in biopharmaceutical and research applications.

Other Meanings for HIC