What Does HIF Stand For?

HIF stands for Hypoxia Inducible Factor

HIF, or Hypoxia Inducible Factor, is a key regulatory protein complex that responds to low oxygen levels in cellular environments. It plays a crucial role in the cellular adaptation to hypoxia by activating the transcription of genes involved in angiogenesis, energy metabolism, and cell survival. HIF is composed of alpha and beta subunits, with the alpha subunit being stabilized and activated under hypoxic conditions. Dysregulation of HIF is implicated in various diseases, including cancer, where it can promote tumor growth and metastasis.