What Does HNE Stand For?

HNE stands for Human Neutrophil Elastase

Human Neutrophil Elastase (HNE) is an enzyme primarily produced by neutrophils, a type of white blood cell. It plays a crucial role in the immune response by degrading extracellular matrix proteins and modulating inflammation. Dysregulation of HNE activity is associated with various pathological conditions, including chronic obstructive pulmonary disease (COPD), cystic fibrosis, and inflammation-related diseases. HNE serves as a biomarker for certain diseases and is a potential therapeutic target for managing inflammatory disorders.