What Does HNF Stand For?

HNF stands for Hepatocyte Nuclear Factor

HNF, or Hepatocyte Nuclear Factor, refers to a group of transcription factors that play a crucial role in the regulation of gene expression in liver cells (hepatocytes) and other tissues. These factors are essential for maintaining liver function, including glucose metabolism, lipid metabolism, and the production of serum proteins. Mutations in HNF genes can lead to a variety of metabolic disorders, such as maturity-onset diabetes of the young (MODY) and other liver-related diseases. HNFs are vital for the development and functionality of the endocrine and exocrine systems.