What Does HSQC Stand For?

HSQC stands for Heteronuclear Single Quantum Coherence

HSQC, or Heteronuclear Single Quantum Coherence, is a sophisticated nuclear magnetic resonance (NMR) spectroscopy technique used to study the interactions between different nuclei, typically hydrogen (1H) and carbon (13C) or nitrogen (15N). This method allows researchers to obtain detailed structural information about molecules by correlating the signals of heteronuclei, making it particularly valuable in fields such as biochemistry and structural biology for characterizing proteins and complex organic compounds. HSQC provides insights into molecular dynamics and the connectivity of atoms within a molecule, enhancing the understanding of chemical behavior and interactions.