What Does MRD Stand For?

MRD stands for Multiple Rising Dose

MRD, or Multiple Rising Dose, refers to a pharmacological study design in which a series of increasing doses of a drug are administered to subjects over a specified period. This approach is utilized to evaluate the drug's safety, tolerability, pharmacokinetics, and pharmacodynamics, allowing researchers to determine the optimal dosing range for further clinical trials. MRD studies are essential in the drug development process, particularly in the early stages, to inform dosage recommendations and ensure patient safety.