What Does NPTII Stand For?

NPTII stands for Neomycin Phosphotransferase II

NPTII, or Neomycin Phosphotransferase II, is an enzyme that confers resistance to aminoglycoside antibiotics, particularly neomycin. It achieves this by enzymatically phosphorylating the drug, thereby rendering it ineffective. NPTII is commonly utilized as a selectable marker in genetic engineering, particularly in transgenic plants, allowing for the identification and selection of successfully transformed cells. Its application facilitates advancements in agricultural biotechnology by enabling the development of crops with enhanced resistance to herbicides and pests.