What Does PAM Stand For?
PAM stands for Peptidylglycine Alpha Amidating Monooxygenase
PAM, or Peptidylglycine Alpha Amidating Monooxygenase, is a critical enzyme involved in the post-translational modification of peptides. It catalyzes the conversion of peptidylglycines into their amidated forms, which are essential for the biological activity of various neuropeptides and hormones. PAM plays a key role in the regulation of various physiological processes, including neurotransmission and hormonal signaling, and is significant in the context of various physiological and pathological conditions. Its activity relies on the availability of copper and ascorbate as cofactors, highlighting its importance in metabolic pathways.
Added on 14th April 2008 | Last edited on 16th June 2025 | Edit Acronym