What Does PBPK Stand For?

PBPK stands for Physiologically Based Pharmacokinetic

PBPK, or Physiologically Based Pharmacokinetic modeling, is a scientific approach used to predict the absorption, distribution, metabolism, and excretion of chemicals and pharmaceuticals in biological systems. By integrating biological and physiological parameters with drug-specific data, PBPK models simulate human and animal responses to various substances, facilitating drug development, risk assessment, and regulatory evaluations. This method enhances the understanding of drug dynamics, ultimately supporting more informed decision-making in pharmacology and toxicology.