What Does PBTK Stand For?

PBTK stands for Physiologically Based Toxicokinetics

PBTK, or Physiologically Based Toxicokinetics, refers to a modeling approach used to predict the absorption, distribution, metabolism, and excretion of chemical substances in biological systems. This framework integrates physiological parameters and biological data to simulate how chemicals interact with the body, enhancing the understanding of their potential effects on human health and the environment. PBTK models are valuable tools in risk assessment, regulatory decision-making, and pharmaceutical development, enabling more accurate predictions of toxicokinetic behavior across different populations and exposure scenarios.