What Does PKG Stand For?

PKG stands for Protein Kinase G

PKG, or Protein Kinase G, is a serine/threonine kinase that plays a crucial role in various cellular processes by mediating the effects of cyclic GMP (cGMP). It exists in two main isoforms, PKG I and PKG II, which are involved in regulating smooth muscle relaxation, cell proliferation, and apoptosis. PKG participates in signaling pathways that influence cardiovascular function, neuronal signaling, and immune responses, making it a significant target for therapeutic interventions in various diseases.

Other Meanings for PKG