What Does PRPP Stand For?

PRPP stands for Phosphoribosyl Pyrophosphate

PRPP, or Phosphoribosyl Pyrophosphate, is a critical biochemical compound involved in nucleotide synthesis and metabolism. It serves as a key substrate in the biosynthesis of purine and pyrimidine nucleotides, playing a vital role in cellular processes such as DNA and RNA synthesis. PRPP is generated from ribose-5-phosphate and ATP through the action of the enzyme PRPP synthetase, and its regulation is crucial for maintaining nucleotide pool balance within cells.