What Does SIBFA Stand For?

SIBFA stands for Sum Of Interactions Between Fragments Computed Ab Initio

SIBFA, or Sum Of Interactions Between Fragments Computed Ab Initio, is a computational chemistry method that quantifies the interactions between molecular fragments by employing ab initio quantum mechanical calculations. This approach allows for the accurate assessment of molecular properties and behaviors by systematically analyzing the contributions of individual fragments, thereby facilitating the investigation of complex systems with improved precision and efficiency. SIBFA is particularly useful in studying large biomolecules and materials, offering insights into their structural and energetic characteristics.