What Does TACE Stand For?

TACE stands for Tumor Necrosis Factor Alpha Converting Enzyme

TACE, or Tumor Necrosis Factor Alpha Converting Enzyme, is a metalloproteinase enzyme that plays a crucial role in the regulation of inflammatory responses. It is primarily involved in the cleavage of membrane-bound precursor proteins, releasing bioactive molecules like tumor necrosis factor-alpha (TNF-alpha). By modulating cytokine availability, TACE influences various physiological and pathological processes, including immune response, cancer progression, and tissue remodeling. Therapeutic targeting of TACE is being explored for its potential in treating inflammatory diseases and cancer.