What Does TBP Stand For?

TBP stands for TATA Box Binding Protein

TBP, or TATA Box Binding Protein, is a pivotal transcription factor that plays a crucial role in the initiation of gene transcription in eukaryotic organisms. It binds specifically to the TATA box, a conserved sequence found in the promoter region of many genes, facilitating the recruitment of other transcription factors and RNA polymerase II to the promoter. By establishing the transcription initiation complex, TBP is essential for the expression of a wide array of genes, influencing various biological processes, including development and cellular responses to environmental changes. Dysregulation of TBP function is associated with several diseases, underscoring its importance in gene regulation.

Other Meanings for TBP