What Does TFPI Stand For?

TFPI stands for Tissue Factor Pathway Inhibitor

TFPI, or Tissue Factor Pathway Inhibitor, is a pivotal protein involved in the regulation of blood coagulation. It functions primarily by inhibiting the tissue factor/factor VIIa complex, thereby modulating the extrinsic pathway of coagulation and preventing excessive thrombus formation. TFPI plays a crucial role in maintaining hemostasis and is a key component in the body's natural anticoagulant mechanisms. Its dysregulation can contribute to various thromboembolic disorders, making it an important target for therapeutic interventions in coagulation-related diseases.