What Does TIRM Stand For?

TIRM stands for Total Internal Reflection Microscopy

Total Internal Reflection Microscopy (TIRM) is an advanced imaging technique that exploits the phenomenon of total internal reflection to achieve high-resolution visualization of samples. By employing evanescent waves generated at the interface between two media, TIRM enables the observation of structures and dynamics at the nanometer scale, particularly at or near the surface of a specimen. This non-invasive method is widely utilized in biological research, materials science, and nanotechnology for studying surface interactions, molecular dynamics, and cellular processes with minimal background noise.