What Does TNFR Stand For?

TNFR stands for Tumor Necrosis Factor Receptor

TNFR, or Tumor Necrosis Factor Receptor, refers to a group of receptor proteins that play a crucial role in mediating the effects of tumor necrosis factor (TNF), a cytokine involved in systemic inflammation and immune responses. TNFRs are integral to various physiological processes, including cell proliferation, differentiation, and apoptosis. There are two main types: TNFR1 and TNFR2, each with distinct functions and signaling pathways. Dysregulation of TNFR signaling is associated with several diseases, including autoimmune disorders, cancer, and chronic inflammatory conditions, making them significant targets for therapeutic interventions.