What Does TNFR1 Stand For?

TNFR1 stands for Tumor Necrosis Factor Receptor 1

TNFR1, or Tumor Necrosis Factor Receptor 1, is a cell surface receptor that plays a critical role in the immune system by mediating the effects of tumor necrosis factor (TNF), a pro-inflammatory cytokine. TNFR1 is involved in various cellular processes, including apoptosis, cell proliferation, and inflammation. It is expressed on many cell types and is significant in the pathogenesis of autoimmune diseases, cancer, and other inflammatory conditions. Understanding TNFR1 signaling pathways is crucial for developing therapeutic strategies targeting TNF-related diseases.