What Does TPSA Stand For?
TPSA stands for Topological Surface Area
TPSA, or Topological Surface Area, is a quantitative measure used in cheminformatics and molecular modeling to characterize the spatial dimensions and properties of molecular surfaces. It represents the surface area of a molecule that is accessible to solvent or potential interactions, taking into account the geometric arrangement of atoms. TPSA is an important parameter in drug design and development, as it can influence the solubility, permeability, and overall bioavailability of pharmaceutical compounds.
Added on 14th April 2008 | Last edited on 16th June 2025 | Edit Acronym