What Does TRAIL Stand For?

TRAIL stands for Tumor Necrosis Factor Related Apoptosis Inducing Ligand

TRAIL, or Tumor Necrosis Factor Related Apoptosis Inducing Ligand, is a cytokine that plays a critical role in apoptosis, specifically in inducing programmed cell death in cancer cells. As part of the tumor necrosis factor (TNF) superfamily, TRAIL interacts with its receptors to activate intracellular signaling pathways that lead to cell death, making it a key target in cancer research and therapy. Its ability to selectively induce apoptosis in malignant cells while sparing normal cells offers significant potential for developing targeted cancer treatments.