What Does TRCF Stand For?

TRCF stands for Transcription Repair Coupling Factor

Transcription Repair Coupling Factor (TRCF) is a protein complex that plays a crucial role in the coordination of transcription and DNA repair processes. It enhances the efficiency of nucleotide excision repair by facilitating the repair of damaged DNA while transcription is ongoing. By linking transcription machinery with the repair pathways, TRCF helps maintain genomic stability and proper gene expression, thereby playing a significant role in cellular responses to DNA damage.