What Does VNS Stand For?

VNS stands for Vicarious Nucleophilic Substitution

Vicarious Nucleophilic Substitution (VNS) is a chemical reaction mechanism in which a nucleophile substitutes one atom or group in a substrate with a different nucleophilic species, typically through an intermediary that allows for the transfer of reactive sites. This process enables the modification of complex organic compounds while preserving the integrity of the molecular framework, making it a valuable strategy in synthetic organic chemistry and the development of pharmaceuticals. VNS is characterized by its ability to incorporate diverse functional groups, enhancing the versatility and specificity of chemical transformations.