What Does CREB Stand For?
CREB stands for CAMP Responsive Element Binding
CREB, or CAMP Responsive Element Binding, is a transcription factor that plays a crucial role in gene expression regulation. It is activated by cellular signaling pathways, particularly those involving cyclic AMP (cAMP). Once activated, CREB binds to specific DNA sequences known as cAMP response elements (CRE), facilitating the transcription of target genes. This mechanism is essential for various physiological processes, including neuronal function, metabolism, and cell survival, and is implicated in numerous diseases, including cancer and neurological disorders.
Added on 14th April 2008 | Last edited on 17th June 2025 | Edit Acronym