What Does CREB Stand For?

CREB stands for Cyclic AMP Response Element Binding Protein

Cyclic AMP Response Element Binding Protein (CREB) is a cellular transcription factor that plays a crucial role in regulating gene expression in response to signaling molecules, primarily through the activation of cyclic AMP (cAMP). It binds to specific DNA sequences known as cAMP response elements (CRE) to modulate the transcription of target genes involved in processes such as neuronal plasticity, cell survival, and metabolism. CREB is important for various physiological functions and is implicated in several pathological conditions, including cancer and neurodegenerative diseases.

Added on 14th April 2008 | Last edited on 17th June 2025 | Edit Acronym

Other Meanings for CREB